Immunoglobulin theories

 

Immunoglobulins: They are antibodies that are produced by B cells which are a lymphocyte. They function in neutralizing foreign substances that invade the body such as bacteria and viruses. They are Y- shaped structures that have heavy chains and light chains.

http://myplace.frontier.com/~dffix/medmicro/igs.htm

 

Germ- line theory: This theory states that each immunoglobulin has genetic information that is encoded in the germ- line genome.

Somatic mutation theory: This theory is based on the limited amount of inherited antibodies that undergo a mutation with their B cells to generate the observed repertoire
 
http://nsdl.niscair.res.in/bitstream/123456789/546/1/AntibodyDiversity.pdf 
http://www.nature.com/icb/journal/v86/n2/fig_tab/7100160f1.html